You need to use the FileSystemObject of the Scripting Runtime library. See
here. This library is not part of the standard VB references by default so remember you will have to find it in the "References" list and check it so that it is added to your project; it is under "References" as "Microsoft Scripting Runtime Library". However bear in mind that calls to delete files from a VB app are high-level requests to the O/S, not direct kernel commands. If you have any kind of file lock contention you won't be able to delete a given file.
The best way to blast an entire drive would be use the DOS 'format' command. You cannot run 'format' though on the system drive, and it will take longer to format a drive than to erase all files, though formatting will really do it. You would use the Shell command in VB to execute the DOS command.
See
here and
here.
You can also use the Shell command to execute the "del" DOS command recursively against the drive. The FileSystemObject is basically doing that under the covers, so it's not too far away. Finally, you can use API code to do it, though I am guessing you are not quite there yet in your experience. But if so, take a look at these articles:
http://allapi.mentalis.org/vbtutor/iapi2.shtmlhttp://www.devarticles.com/c/a/Visual-Basic/Accessing-the-Windows-API-in-Visual-Basic/2/